ADGRL4


Introducing ADGRL4: The Crucial Receptor in Human Biology

Description:

ADGRL4 (adhesion G protein-coupled receptor L4) is a cell surface receptor that plays a vital role in various physiological processes. It belongs to the adhesion GPCR family, characterized by their function in cell-cell communication and adhesion. ADGRL4 is widely expressed throughout the body, including the brain, immune cells, and endothelial cells.

Associated Diseases:

Dysregulation of ADGRL4 has been linked to several diseases and conditions, such as:

  • Neuropsychiatric disorders: ADGRL4 is implicated in the pathogenesis of schizophrenia, bipolar disorder, and autism spectrum disorder.
  • Autoimmune diseases: Reduced ADGRL4 expression has been associated with autoimmune disorders such as rheumatoid arthritis and lupus.
  • Cancer: Alterations in ADGRL4 expression have been observed in various cancers, including breast, lung, and colon cancer.

Did you Know ?

A recent study found that individuals with schizophrenia have significantly lower levels of ADGRL4 in the brain compared to healthy controls. This suggests that ADGRL4 may play a role in the development and progression of schizophrenia.



Disclaimer: The information provided here is not exhaustive by any means. Always consult your doctor or other qualified healthcare provider with any questions you may have regarding a medical condition, procedure, or treatment, whether it is a prescription medication, over-the-counter drug, vitamin, supplement, or herbal alternative.