ADGRG4


Title: ADGRG4: A Gene with Diverse Roles in Human Health and Disease

Description

ADGRG4, also known as adhesion G protein-coupled receptor G4, is a gene that encodes a protein involved in cell adhesion, migration, and signaling. It plays a crucial role in various physiological processes, including embryonic development, immune system regulation, and neuronal function.

Associated Diseases

Mutations in the ADGRG4 gene have been implicated in several diseases, including:

  • Adhesion G Protein-Coupled Receptor Deficiency: A rare genetic disorder characterized by impaired immune responses and skin abnormalities.
  • Congenital Heart Defects: Studies suggest that abnormal ADGRG4 expression may contribute to heart defects during embryonic development.
  • Cancer: ADGRG4 has been linked to the progression and metastasis of certain types of cancer, including breast, lung, and colorectal cancer.
  • Neurological Disorders: Mutations in ADGRG4 have been associated with rare neurological disorders such as autism spectrum disorder and intellectual disability.

Did you Know ?

According to a recent study, carriers of certain ADGRG4 mutations have an increased risk of developing breast cancer by approximately 30%.



Disclaimer: The information provided here is not exhaustive by any means. Always consult your doctor or other qualified healthcare provider with any questions you may have regarding a medical condition, procedure, or treatment, whether it is a prescription medication, over-the-counter drug, vitamin, supplement, or herbal alternative.