ADC
Description
The ADC gene, encoding the adenosine deaminase complex, plays a crucial role in the immune system by controlling the levels of adenosine, a potent immunosuppressive molecule. Adenosine deaminase complex (ADA) is an enzyme that catalyzes the deamination of adenosine to inosine, a reaction that is essential for the proper function of the immune system. Deficiencies in ADA can lead to severe combined immunodeficiency (SCID), a life-threatening condition characterized by a complete absence of T-cell and B-cell function. The ADC gene is therefore of great importance in understanding the regulation of immune responses and the development of new therapeutic strategies.
Associated Diseases
Did you know?
The first gene therapy trial for SCID, conducted in 1990, involved the introduction of a functional copy of the ADA gene into patients‘ cells.
