ACTL8
Actl8: A Muscle Protein Linked to Health and Disease
Description:
Actl8 (Actin-like protein 8) is a muscle-specific protein that plays a crucial role in muscle structure and function. It belongs to the actin family of proteins known for their roles in cell movement, cell division, and muscle contraction. Actl8 is present in various muscle types, including skeletal, cardiac, and smooth muscles.
Associated Diseases:
Dysregulation of Actl8 expression has been linked to several diseases, including:
- Muscle weakness: Mutations or deficiencies in Actl8 can lead to muscle weakness, atrophy, and impaired mobility.
- Cardiomyopathy: Abnormalities in Actl8 have been associated with certain forms of cardiomyopathy, a condition that affects the heart muscle.
- Neuromuscular disorders: Some neuromuscular disorders, such as myasthenia gravis and Lambert-Eaton syndrome, have shown altered Actl8 levels.
Did you Know ?
- Research suggests that Actl8 levels decline with age, contributing to muscle weakness and sarcopenia (age-related loss of muscle mass).
