ABCF2
ABCF2: A Gene Essential for Lung Development and Function
Description
ABCF2, also known as the ATP-binding cassette sub-family F member 2, is a gene that encodes a protein crucial for the development and function of the lungs. It plays a vital role in the transport of molecules across cell membranes, ensuring proper fluid balance and surfactant secretion in the airways.
Associated Diseases
Mutations in the ABCF2 gene have been linked to several lung diseases, including:
- Pulmonary Fibrosis: A progressive and fatal disease characterized by scarring and thickening of lung tissue.
- Idiopathic Pulmonary Fibrosis (IPF): A specific type of pulmonary fibrosis with an unknown cause.
- Acute Exacerbation of Idiopathic Pulmonary Fibrosis (AE-IPF): A sudden worsening of symptoms in patients with IPF.
Did you Know ?
Approximately 5-10% of IPF cases are caused by mutations in the ABCF2 gene. This makes it one of the most common genetic factors associated with the disease.
