ABCC5-AS1
abcc5-as1: A Long Non-Coding RNA with Potential Roles in Cancer and Other Diseases
Description
abcc5-as1 is a long non-coding RNA (lncRNA) located on chromosome 3q26.32. LncRNAs are a class of RNA molecules that are greater than 200 nucleotides in length and do not code for proteins. They have been found to play important roles in various biological processes, including gene regulation, cell differentiation, and disease development.
abcc5-as1 has been shown to be involved in the regulation of various cellular processes, including cell proliferation, apoptosis, and migration. It has also been implicated in the development of several diseases, including cancer, cardiovascular disease, and neurological disorders.
Associated Diseases
Cancer:
abcc5-as1 has been found to be overexpressed in several types of cancer, including lung cancer, breast cancer, and colorectal cancer. Overexpression of abcc5-as1 has been associated with increased cell proliferation, invasion, and metastasis.
Cardiovascular disease:
abcc5-as1 has been shown to be involved in the development of atherosclerosis, a major risk factor for heart disease and stroke. Overexpression of abcc5-as1 has been associated with increased inflammation and lipid accumulation in the arteries.
Neurological disorders:
abcc5-as1 has been implicated in the development of Alzheimer‘s disease and Parkinson‘s disease. Overexpression of abcc5-as1 has been associated with increased neuronal damage and inflammation in the brain.
Did you Know ?
According to a recent study, overexpression of abcc5-as1 was found in over 70% of lung cancer patients. The study also found that patients with high levels of abcc5-as1 had a significantly shorter overall survival time than patients with low levels of abcc5-as1.
