ZBTB11
Description
The ZBTB11 gene, also known as Zinc Finger and BTB Domain Containing 11, encodes a transcription factor that plays a crucial role in regulating the development and function of immune cells. ZBTB11 acts as a master regulator, controlling the expression of a wide range of genes involved in immune responses. It is involved in the differentiation of various immune cell lineages, including T cells, B cells, and natural killer (NK) cells. ZBTB11 also regulates the activation and function of mature immune cells, influencing their ability to mount an effective immune response.
Associated Diseases
- Immune deficiency disorders: Mutations in ZBTB11 have been linked to various immune deficiencies, characterized by impaired immune responses and increased susceptibility to infections.
- Autoimmune diseases: Dysregulation of ZBTB11 activity has been implicated in autoimmune diseases, where the immune system mistakenly attacks healthy tissues.
- Cancer: ZBTB11 has been found to be involved in the development and progression of certain types of cancers, including leukemia and lymphoma.
Did you know?
ZBTB11 is highly conserved across species, suggesting its essential role in immune system function.
