WDR45B

Description

WDR45B, also known as WD repeat-containing protein 45B, is a gene that encodes a protein playing a crucial role in various cellular processes. The protein interacts with different cellular components, including the cytoskeleton, DNA, and other proteins, suggesting its involvement in diverse biological pathways. WDR45B mutations have been linked to several human diseases, highlighting its importance in maintaining cellular function.

Associated Diseases

• Neurodevelopmental disorders (e.g., intellectual disability, autism spectrum disorder)
• Cancer (e.g., leukemia, lymphoma)
• Cardiovascular disease
• Metabolic disorders (e.g., diabetes)
• Neurodegenerative diseases (e.g., Alzheimer‘s disease, Parkinson‘s disease)

Did you know?

WDR45B is highly expressed in the brain, suggesting its critical role in neuronal function and development.