VEGFA
Description
The VEGFA gene (Vascular Endothelial Growth Factor A) plays a crucial role in angiogenesis, the formation of new blood vessels. It encodes a protein that acts as a potent signaling molecule, stimulating the growth, migration, and permeability of blood vessels. VEGFA is essential for normal development, wound healing, and tissue repair. Its dysregulation can lead to various diseases, including cancer, cardiovascular disease, and diabetic retinopathy.
Associated Diseases
- Cancer (tumor growth and metastasis)
- Cardiovascular Disease (atherosclerosis, heart failure)
- Diabetic Retinopathy (retinal vascular leakage)
- Macular Degeneration (age-related)
- Preeclampsia (pregnancy complication)
- Rheumatoid Arthritis (inflammation)
- Psoriasis (skin inflammation)
Did you know?
VEGFA is also involved in the development of the placenta during pregnancy, ensuring adequate blood supply to the fetus.