VARS1
Description
VARS1, also known as valyl-tRNA synthetase, plays a crucial role in protein synthesis. It acts as a molecular machine, attaching the amino acid valine to its corresponding transfer RNA (tRNA). This process, known as aminoacylation, ensures that the correct amino acid is incorporated into the growing polypeptide chain during translation. VARS1 is essential for the production of all proteins in the body, highlighting its fundamental importance in cellular function and organismal development.
Associated Diseases
- Charcot-Marie-Tooth disease type 2Z (CMT2Z)
- Proximal spinal muscular atrophy type 2 (SMA2)
- Autosomal dominant optic atrophy (ADOA)
- Other neurological disorders
Did you know?
Mutations in the VARS1 gene have been linked to a wide range of neurological disorders, demonstrating its critical role in maintaining proper nervous system function.
