TXNL4A : thioredoxin like 4A
Description
The TXNL4A (thioredoxin like 4A) is a protein-coding gene located on chromosome 18.
The TXNL4A gene provides instructions for making one part (subunit) of a protein complex called the major spliceosome, which is the larger of two types of spliceosomes found in human cells. Spliceosomes help process messenger RNA (mRNA), which is a chemical cousin of DNA that serves as a genetic blueprint for making proteins. The spliceosomes recognize and then remove regions called introns to help produce mature mRNA molecules from immature mRNA molecules.
TXNL4A is involved in pre-mRNA splicing by being a component of the U5 snRNP and U4/U6-U5 tri-snRNP complexes, which are essential for spliceosome assembly. It also plays a role in the precatalytic spliceosome (spliceosome B complex).
TXNL4A is also known as BMKS, DIB1, DIM1, SNRNP15, TXNL4, U5-15kD.
