TNXB : tenascin XB
Description
The TNXB (tenascin XB) is a protein-coding gene located on chromosome 6.
The TNXB gene provides instructions for making tenascin-X, a protein crucial for organizing and maintaining connective tissues, which support muscles, joints, organs, and skin. Studies suggest that tenascin-X regulates the production and assembly of certain collagens, proteins that strengthen connective tissues. It also plays a role in regulating the structure and stability of elastic fibers, providing flexibility to connective tissues.
Tenascin-X (TN-X) mediates interactions between cells and the extracellular matrix. It inhibits cell migration, accelerates collagen fibril formation, and may support the growth of epithelial tumors.
TNXB is also known as EDS3, EDSCLL, EDSCLL1, HXBL, TENX, TN-X, TNX, TNXB1, TNXB2, TNXBS, VUR8, XB, XBS.
Associated Diseases
- Vesicoureteral reflux 8
- Classical-like Ehlers-Danlos syndrome type 1
- Ehlers-Danlos syndrome, classic-like
- Ehlers-Danlos syndrome
