SLC52A2 : solute carrier family 52 member 2
Description
The SLC52A2 (solute carrier family 52 member 2) is a protein-coding gene located on chromosome 8.
The SLC52A2 gene provides instructions for making the RFVT2 protein, a riboflavin transporter. This protein facilitates the movement of riboflavin across cell membranes, particularly in brain and spinal cord cells. Riboflavin is essential for the synthesis of FAD and FMN, coenzymes crucial for various cellular processes, including energy production and the breakdown of carbohydrates, fats, and proteins.
SLC52A2 is a plasma membrane transporter responsible for the uptake of riboflavin (vitamin B2) into cells. Riboflavin plays a crucial role in various biochemical oxidation-reduction reactions essential for carbohydrate, lipid, and amino acid metabolism. Humans cannot synthesize riboflavin and must obtain it through intestinal absorption. SLC52A2 may also act as a receptor for 4-hydroxybutyrate.
SLC52A2 is also known as BVVLS2, D15Ertd747e, GPCR41, GPR172A, HuPAR-1, PAR1, RFT3, RFVT2, hRFT3.
