SLC45A1
Description
The SLC45A1 (solute carrier family 45 member 1) is a protein-coding gene located on chromosome 1.
SLC45A1 is a member of the SLC45 family of solute carriers. Analysis of the protein function in a recombinant yeast expression assay show that it can: (i) transport a disaccharide, such as glucose and sucrose, (ii) perform secondary active transport in a proton-dependent manner. It is associated with sugar transport in the brain, and rare mutations in the gene are associated with intellectual disability and epilepsy. Analogous to the effect of mutation of the cerebral glucose transporter GLUT1 (SLC2A1).
SLC45A1 is also known as DNB5, IDDNPF, PAST-A.
