SLC25A22


Description

SLC25A22, also known as the mitochondrial dicarboxylate carrier (DIC), is a gene that encodes a protein responsible for transporting dicarboxylate substrates, such as malate, fumarate, and succinate, across the inner mitochondrial membrane. This transport is crucial for various metabolic pathways, including the tricarboxylic acid (TCA) cycle and gluconeogenesis. SLC25A22 plays a key role in regulating energy production and maintaining cellular homeostasis. The gene is located on chromosome 19q13.32 and spans approximately 12.5 kilobases.

Associated Diseases

Did you know?

SLC25A22 is essential for the proper functioning of the citric acid cycle, a central metabolic pathway responsible for generating energy in the form of ATP.


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