SCO2

Description

SCO2, short for cytochrome c oxidase assembly protein 2, is a crucial enzyme involved in the assembly of cytochrome c oxidase (COX), the terminal enzyme in the mitochondrial electron transport chain. This complex process is essential for cellular respiration, where energy is derived from glucose and oxygen. SCO2‘s primary function is to facilitate the insertion of copper ions into COX, a vital step in the enzyme‘s maturation and proper function. Dysfunction in SCO2 can lead to various mitochondrial disorders, highlighting its critical role in cellular energy production.

Associated Diseases

• Leigh Syndrome
• Mitochondrial Myopathy
• Cardiomyopathy
• Hepatic Failure
• Neurodevelopmental Delay
• Cerebral Palsy

Did you know?

SCO2 is a highly conserved protein, meaning its structure and function are similar across various species, suggesting its fundamental importance in cellular life.