SARS1
Description
The SARS1 gene, also known as the transmembrane serine protease 2 (TMPRSS2) gene, is a crucial player in the human respiratory system. It encodes an enzyme that plays a vital role in activating certain viruses, including SARS-CoV-2, the virus responsible for COVID-19. TMPRSS2 cleaves the spike protein of the virus, facilitating its entry into cells. This gene is located on chromosome 21 and consists of 10 exons. Understanding its structure, function, and associated diseases is essential for developing effective therapeutic interventions.
Associated Diseases
Did you know?
TMPRSS2 expression is higher in the male reproductive tract, which explains its potential link to prostate cancer.