RRP7A
Description
The RRP7A (ribosomal RNA processing 7 homolog A) is a protein-coding gene located on chromosome 22.
RRP7A is a nucleolar protein that plays a crucial role in ribosomal RNA (rRNA) processing. It contributes to the formation of the small subunit (SSU) processome, which is the first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome, RRP7A interacts with other ribosome biogenesis factors, an RNA chaperone, and ribosomal proteins to facilitate RNA folding, modifications, rearrangements, and cleavage. RRP7A also participates in targeted degradation of pre-ribosomal RNA through the RNA exosome. In addition to its role in ribosome biogenesis, RRP7A is involved in primary cilia resorption and cell cycle progression during neurogenesis and neocortex development.
RRP7A is also known as BK126B4.3, CGI-96, MCPH28, Rrp7.
