RARS2 : arginyl-tRNA synthetase 2, mitochondrial


Description

The RARS2 (arginyl-tRNA synthetase 2, mitochondrial) is a protein-coding gene located on chromosome 6.

The RARS2 gene provides instructions for making an enzyme called mitochondrial arginyl-tRNA synthetase, which is active in mitochondria, the energy-producing structures within cells. This enzyme works with transfer RNA (tRNA), a molecule similar to DNA, to assemble amino acids into proteins. Mitochondrial arginyl-tRNA synthetase specifically links the amino acid arginine to tRNA, enabling the incorporation of arginine into new proteins within mitochondria.

RARS2 catalyzes the attachment of arginine to tRNA(Arg) through a two-step process. First, arginine is activated by ATP to form Arg-AMP. Then, this activated arginine is transferred to the acceptor end of tRNA(Arg).

RARS2 is also known as ArgRS, DALRD2, PCH6, PRO1992, RARSL.

Associated Diseases


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