PTPN23
Description
The PTPN23 gene provides instructions for making a protein called protein tyrosine phosphatase non-receptor type 23. This enzyme plays a crucial role in the immune system by regulating the activity of other proteins involved in immune cell signaling. PTPN23 dephosphorylates tyrosine residues on specific target proteins, effectively turning them off and influencing a range of immune responses. The gene‘s importance lies in its role in maintaining immune homeostasis and preventing autoimmune disorders.
Associated Diseases
- Systemic lupus erythematosus (SLE)
- Rheumatoid arthritis (RA)
- Type 1 diabetes
- Multiple sclerosis (MS)
- Inflammatory bowel disease (IBD)
- Crohn‘s disease
- Ulcerative colitis
Did you know?
Genetic variations in the PTPN23 gene have been associated with an increased risk of developing autoimmune diseases, suggesting a complex interplay between genetics and environmental factors in disease susceptibility.
