PRG4


Description

The PRG4 gene encodes a protein called lubricin, a major component of synovial fluid that plays a crucial role in joint lubrication and protection. Lubricin reduces friction between cartilage surfaces, allowing smooth joint movement and preventing wear and tear. It also possesses anti-inflammatory properties, contributing to joint health. Mutations in the PRG4 gene can lead to various joint disorders characterized by pain, stiffness, and reduced mobility.

Associated Diseases

Did you know?

Lubricin is one of the most slippery substances known, with a friction coefficient lower than ice on ice.


Disclaimer: The information provided here is not exhaustive by any means. Always consult your doctor or other qualified healthcare provider with any questions you may have regarding a medical condition, procedure, or treatment, whether it is a prescription medication, over-the-counter drug, vitamin, supplement, or herbal alternative.