PRDM12
Description
PRDM12, a gene encoding a zinc finger protein, plays a crucial role in regulating immune responses. Its protein product acts as a transcriptional repressor, influencing the expression of genes involved in immune cell differentiation, cytokine production, and inflammation. Aberrant PRDM12 activity has been linked to various immune disorders, highlighting its importance in maintaining immune homeostasis. Research on PRDM12 continues to unveil its complex functions and potential as a therapeutic target.
Associated Diseases
- Autoimmune diseases (e.g., Systemic lupus erythematosus, Rheumatoid arthritis)
- Inflammatory bowel disease (IBD)
- Cancer (e.g., Multiple myeloma, Leukemia)
- Infections
Did you know?
PRDM12 has been shown to regulate the expression of microRNAs, small non-coding RNAs that play a critical role in gene regulation.
