PNPLA8
Description
The PNPLA8 gene encodes patatin-like phospholipase domain-containing protein 8, an enzyme playing a crucial role in lipid metabolism. It is involved in the hydrolysis of triglycerides and other lipids, contributing to energy production and maintaining lipid homeostasis. PNPLA8 is expressed in various tissues, including the liver, adipose tissue, and pancreas, highlighting its widespread influence on lipid metabolism. Mutations in the PNPLA8 gene have been linked to several diseases, particularly those affecting lipid metabolism and energy balance.
Associated Diseases
Did you know?
Studies have shown that PNPLA8 expression is influenced by dietary factors, including the consumption of saturated and unsaturated fatty acids.
