PLG : plasminogen

Description

The PLG gene provides instructions for making plasminogen, a protein that plays a vital role in the breakdown of blood clots. Plasminogen is converted to plasmin, an enzyme that dissolves clots, ensuring proper blood flow. This process is essential for maintaining cardiovascular health. Variations in the PLG gene can affect the efficiency of clot dissolution, potentially influencing the risk of developing blood clots.

Associated Diseases

• Deep vein thrombosis (DVT)
• Pulmonary embolism (PE)
• Stroke
• Heart attack
• Venous insufficiency
• Fibrinolysis disorders
• Cancer
• Pregnancy complications

Did you know?

PLG gene mutations are associated with an increased risk of developing venous thromboembolism (VTE), a condition involving blood clots in the veins.