PLA2G7

Description

PLA2G7, also known as group VII phospholipase A2, is a gene that encodes an enzyme involved in the breakdown of phospholipids. This enzyme plays a crucial role in various biological processes, particularly in the nervous system. PLA2G7 is expressed primarily in the brain and is involved in the production of signaling molecules that regulate neuronal function and inflammation. Mutations in the PLA2G7 gene have been linked to a number of neurological disorders, including neurodegeneration, epilepsy, and neurodevelopmental disorders. Understanding the role of PLA2G7 in these conditions could lead to the development of novel therapies for these diseases.

Associated Diseases

• Infantile neuroaxonal dystrophy (INAD)
• Childhood ataxia with central nervous system hypomyelination (CACH)
• Cerebral palsy
• Epilepsy
• Neurodevelopmental disorders
• Alzheimer's disease
• Parkinson's disease

Did you know?

PLA2G7 is a highly conserved gene, meaning that it has remained relatively unchanged throughout evolution. This suggests that it plays an important role in biological processes that are essential for survival.