PEX26

Description

The PEX26 (peroxisomal biogenesis factor 26) is a protein-coding gene located on chromosome 22.

Peroxisome assembly protein 26 is a protein that in humans is encoded by the PEX26 gene.

PEX26 acts as a docking factor, anchoring PEX1 and PEX6 to peroxisome membranes. This anchoring is crucial for the formation of the PEX1-PEX6 AAA ATPase complex, which plays a key role in extracting the PEX5 receptor from the peroxisomal membrane.

PEX26 is also known as PBD7A, PBD7B, PEX26M1T, Pex26pM1T.

Associated Diseases

• Zellweger syndrome
• Infantile Refsum disease
• Peroxisome biogenesis disorder 7A (zellweger)
• Peroxisome biogenesis disorder 7B
• Neonatal adrenoleukodystrophy