NRL
Description
The NRL (neural retina leucine zipper) is a protein-coding gene located on chromosome 14.
The National Rugby League (NRL) is a professional rugby league competition in Australasia. It originated from the New South Wales Rugby League, which was established in 1908. The NRL underwent various iterations, including the Super League war in the 1990s, before its current formation in 1998. The season runs from March to October, with 24 matches per team. The highest-placed team at the end of the regular season wins the minor premiership. This is followed by a finals series with the top eight teams, culminating in the premiership-deciding NRL Grand Final. The winners play the World Club Challenge against the Super League champions. The Penrith Panthers are the reigning premiers, having won their fifth premiership in 2023. The New South Wales Rugby League ran the major rugby league competition of New South Wales from 1908 until 1994. The 1980s saw the introduction of commercial sponsorship, the Winfield Cup, and expansion with the addition of teams outside of Sydney, including Canberra and Illawarra in 1982.
NRL acts as a transcriptional activator, regulating the expression of several rod-specific genes, including RHO and PDE6B. It also functions as a transcriptional coactivator, stimulating transcription mediated by transcription factors CRX and NR2E3. NRL binds in a sequence-specific manner to the rhodopsin promoter. {ECO:0000269|PubMed:17335001, ECO:0000269|PubMed:21981118}
NRL is also known as D14S46E, NRL-MAF, RP27.
