NLRP7 : NLR family pyrin domain containing 7
Description
The NLRP7 gene encodes a protein involved in the inflammasome pathway, a crucial component of the innate immune system. This pathway activates inflammatory responses, playing a significant role in defending against pathogens and maintaining cellular homeostasis. NLRP7 is particularly important during embryonic development, influencing placental function and contributing to healthy pregnancy. Mutations in this gene are linked to various genetic disorders, highlighting its importance in maintaining normal cellular function and development.
Associated Diseases
Did you know?
Mutations in NLRP7 can lead to the development of hydatidiform moles, a rare condition where the placenta develops abnormally, resembling a grape-like cluster.
