NHLRC2
Description
The NHLRC2 (NHL repeat containing 2) is a protein-coding gene located on chromosome 10.
NHL Repeat Containing Protein 2, or NHLRC2, is a protein encoded by the NHLRC2 gene.
NHLRC2 has also been referred to as Novel NHL Repeat Domain Containing Protein and 1200003F01Rik.
NHLRC2 is located on the positive strand of chromosome 10, at position 10q25.3. The full gene spans 62,533 base pairs (bp). Eleven exons are transcribed in the protein-coding mRNA. There is a second, less prevalent transcript variant of NHLRC2; this non-coding isoform is 522 bp of retained intron.
The translated NHLRC2 protein is 726 amino acids long in humans and has a molecular weight of 79,442.59 g/mol. It has been found in the cytosol, mitochondria, and/or peroxisomes of cells in which it is expressed.
NHLRC2 is a part of the NHL-repeat superfamily of n-bladed beta-propellers. Specifically, NHLRC2 is a 6-bladed beta-propeller. The NHL repeat is found in many eukaryotic and prokaryotic proteins, and is associated with growth factor regulators.
NHLRC2 is also known as FINCA.
