NDUFAF8
Description
The NDUFAF8 gene provides instructions for making a protein crucial for the assembly of mitochondrial complex I, a vital component of the electron transport chain. This complex is responsible for generating energy in the form of ATP, the primary fuel source for cellular processes. NDUFAF8 protein acts as a chaperone, guiding the correct folding and assembly of other proteins that make up complex I. Mutations in the NDUFAF8 gene can disrupt this assembly process, leading to impaired mitochondrial function and various health problems.
Associated Diseases
Did you know?
NDUFAF8 is a highly conserved gene, meaning its sequence is very similar across different species, highlighting its essential role in cellular function.
