NDUFA9
Description
NDUFA9, also known as NADH dehydrogenase [ubiquinone] iron-sulfur protein 9, is a crucial protein involved in cellular respiration. It acts as a subunit of complex I, the first enzyme in the mitochondrial electron transport chain. Complex I plays a pivotal role in converting energy from food into a usable form for the cell. NDUFA9 specifically binds to the iron-sulfur cluster, a critical component for electron transfer within complex I. Mutations in the NDUFA9 gene can lead to defects in mitochondrial function, impacting energy production and cellular health.
Associated Diseases
Did you know?
NDUFA9 is encoded by a gene located on chromosome 11, a chromosome known to harbor genes involved in various cellular functions.
