NDUFA12
Description
NDUFA12 is a crucial gene that codes for a subunit of NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 12, a key component of complex I in the mitochondrial electron transport chain. This complex is responsible for generating ATP, the primary energy source for cellular processes. NDUFA12 plays a critical role in facilitating electron transfer, thereby ensuring efficient energy production within the mitochondria. Mutations in this gene can disrupt the function of complex I, leading to impaired energy metabolism and various health complications.
Associated Diseases
Did you know?
NDUFA12 mutations are often associated with Leigh Syndrome, a severe neurological disorder characterized by progressive brain damage and developmental delays.
