MYORG
Headline: Understanding the Role of MYORG in Health and Disease
Description:
MYORG is a gene that encodes a protein known as myocilin. This protein plays a crucial role in regulating the outflow of fluid from the eye. It is essential for maintaining the correct intraocular pressure (IOP), which is the pressure inside the eye. When the IOP increases, it can lead to a condition called glaucoma, a leading cause of blindness worldwide.
Associated Diseases:
- Glaucoma: Mutations in the MYORG gene are the most common cause of juvenile open-angle glaucoma, a type of glaucoma that affects children and young adults.
- Pigmentary Glaucoma: Mutations in MYORG are also associated with pigmentary glaucoma, which is characterized by the accumulation of pigment granules in the eye.
- Congenital Glaucoma: MYORG mutations can cause congenital glaucoma, which occurs in infants and can lead to severe vision loss.
Did you Know ?
Approximately 3% of all cases of glaucoma are caused by mutations in the MYORG gene, highlighting its significance in the development of this condition.
