MSTO1
Description
MSTO1 (Mesothelin-associated transmembrane protein 1) is a gene that encodes a protein involved in cell growth, differentiation, and adhesion. It is expressed in various tissues, including the mesothelium (the lining of internal organs), epithelial cells, and some tumor cells. The MSTO1 protein interacts with other proteins, such as mesothelin, to regulate cell signaling pathways and influence cellular processes.
Associated Diseases
- Mesothelioma: MSTO1 is often overexpressed in mesothelioma, a type of cancer affecting the lining of the chest or abdomen.
- Ovarian Cancer: High levels of MSTO1 are associated with aggressive ovarian cancer.
- Other Cancers: MSTO1 may be involved in the development of other cancers, including lung, breast, and pancreatic cancer.
- Inflammatory Diseases: MSTO1 has been linked to inflammatory conditions, such as arthritis.
Did you know?
MSTO1 is a potential target for cancer immunotherapy, with antibodies targeting the protein being developed for treatment.
