MPV17 : mitochondrial inner membrane protein MPV17
Description
MPV17, also known as mitochondrial pyruvate carrier 1, is a nuclear-encoded gene that plays a critical role in mitochondrial metabolism. It encodes a protein that forms a transporter embedded in the inner mitochondrial membrane, facilitating the import of pyruvate – a key metabolic intermediate – into the mitochondria. This process is crucial for energy production through the citric acid cycle and oxidative phosphorylation. Mutations in MPV17 can lead to severe mitochondrial disorders, highlighting its importance in cellular respiration and overall health.
Associated Diseases
Did you know?
MPV17 is a highly conserved gene, meaning its sequence is very similar across different species, highlighting its fundamental importance in cellular function.
