MLPH : melanophilin
Description
The MLPH (melanophilin) is a protein-coding gene located on chromosome 2.
The MLPH gene provides instructions for making a protein called melanophilin. This protein is essential for pigmentation, found in melanocytes, the pigment-producing cells. Melanophilin facilitates the transportation of melanosomes, the structures producing melanin, by interacting with proteins from the MYO5A and RAB27A genes. This complex transports melanosomes to the outer edges of melanocytes, where they are transferred to other cells, providing the pigment for normal hair, skin, and eye color.
Melanophilin acts as a key player in transporting melanosomes, the structures that produce melanin, the pigment responsible for skin, hair, and eye color. It links the RAB27A protein on melanosomes to the MYO5A motor protein, facilitating their movement.
MLPH is also known as SLAC2-A.
