MEGF8 : multiple EGF like domains 8
Description
The MEGF8 (multiple EGF like domains 8) is a protein-coding gene located on chromosome 19.
The MEGF8 gene provides instructions for making a protein whose function is unclear. Based on its structure, the Megf8 protein may be involved in cell processes such as attaching cells to one another (cell adhesion) and helping proteins interact with each other. Researchers also suspect that the Megf8 protein plays a role in the normal shaping (patterning) of many parts of the body during embryonic development.
This gene acts as a negative regulator of hedgehog signaling.
MEGF8 is also known as C19orf49, CRPT2, EGFL4, SBP1.
