MEGF10
Description
The MEGF10 gene, located on chromosome 10, encodes a protein known as the multiple EGF-like domains 10 protein. This protein plays a crucial role in cell signaling pathways, particularly those involved in cell adhesion, migration, and proliferation. MEGF10 acts as a receptor, binding to specific ligands on other cells or in the extracellular matrix. This interaction triggers intracellular signaling cascades, ultimately influencing cellular behavior. MEGF10 is highly expressed in various tissues, including the brain, heart, and immune system, suggesting its broad involvement in physiological processes.
Associated Diseases
- Cancer: MEGF10 overexpression has been linked to the progression and metastasis of certain cancers, including breast, lung, and colorectal cancer.
- Neurological Disorders: Dysregulation of MEGF10 expression has been implicated in neurological conditions such as Alzheimer‘s disease and Parkinson‘s disease.
- Immune System Dysregulation: MEGF10 plays a role in immune cell function, and its dysregulation may contribute to autoimmune disorders and inflammation.
Did you know?
MEGF10 is a highly glycosylated protein, meaning it has numerous sugar molecules attached to its structure. These sugar modifications are essential for its proper function.
