MEFV : MEFV innate immunity regulator, pyrin

Description

The MEFV gene,  provides instructions for creating a protein called pyrin. This protein plays a crucial role in regulating inflammation, helping to control the body‘s response to infection and injury. Mutations in the MEFV gene can disrupt this delicate balance, leading to a range of inflammatory disorders. Understanding the MEFV gene and its role in inflammation is essential for diagnosing and managing these conditions effectively.

Associated Diseases

• Familial Mediterranean Fever (FMF)
• Chronic Inflammatory Bowel Disease (IBD)
• Psoriasis
• Rheumatoid Arthritis
• Systemic Lupus Erythematosus (SLE)

Did you know?

The MEFV gene is particularly common in populations of Mediterranean origin, where FMF is more prevalent.