MED27
Description
MED27, also known as Mediator complex subunit 27, plays a crucial role in the intricate world of gene regulation. As a component of the Mediator complex, a vital intermediary between transcription factors and RNA polymerase II, MED27 helps orchestrate the intricate process of gene transcription. This protein acts as a bridge, facilitating the communication between regulatory elements and the molecular machinery that drives gene expression. Its involvement extends beyond transcription, influencing cellular processes like growth, development, and response to environmental cues. While MED27 is essential for normal cellular function, its dysregulation can have profound implications, contributing to the development of various diseases.
Associated Diseases
- Cancer: MED27 dysregulation has been linked to the development and progression of several cancers, including breast cancer, lung cancer, and colorectal cancer.
- Neurodevelopmental Disorders: Mutations in the MED27 gene have been associated with neurodevelopmental disorders like intellectual disability and autism spectrum disorder.
- Cardiovascular Disease: Research suggests a potential link between MED27 dysfunction and cardiovascular disease, highlighting its role in maintaining heart health.
Did you know?
MED27 is highly conserved across different species, suggesting its vital role in fundamental cellular processes.
