MAPKBP1
Description
The MAPKBP1 gene, also known as JNK-binding protein 1, plays a crucial role in cellular signaling pathways. It encodes a protein that interacts with the c-Jun N-terminal kinase (JNK) signaling pathway, a major player in stress responses and cell survival. MAPKBP1 acts as a scaffold protein, bringing together different signaling molecules to facilitate their interaction and regulate downstream signaling events. This intricate interplay is essential for maintaining cellular homeostasis and responding appropriately to environmental cues.
Associated Diseases
- Cancer (e.g., colorectal cancer, breast cancer)
- Neurological disorders (e.g., Alzheimer‘s disease, Parkinson‘s disease)
- Inflammatory diseases (e.g., rheumatoid arthritis, inflammatory bowel disease)
- Cardiovascular diseases
Did you know?
MAPKBP1 is highly expressed in the brain, suggesting its important role in neuronal function and regulation.
