LIPN


Description

The LIPN gene, encodes a protein known as lipin-1, a crucial enzyme involved in the biosynthesis of triacylglycerol (TAG) and phospholipids. Lipin-1 acts as a phosphatidate phosphatase, converting phosphatidic acid (PA) into diacylglycerol (DAG). This reaction is a key step in the synthesis of both TAG and phospholipids, which are essential for various cellular functions, including energy storage, membrane structure, and signal transduction. LIPN gene expression is tightly regulated, ensuring appropriate levels of lipids are produced to meet cellular needs.

Associated Diseases

Did you know?

Lipin-1 is found in various tissues, including liver, adipose tissue, and skeletal muscle, reflecting its widespread role in lipid metabolism.


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