LHCGR : luteinizing hormone/choriogonadotropin receptor

Description

The LHCGR gene provides instructions for making the luteinizing hormone/chorionic gonadotropin receptor, a protein that sits on the surface of cells in the ovaries, testes, and adrenal glands. This receptor plays a vital role in the body's hormonal signaling system, specifically responding to luteinizing hormone (LH) and human chorionic gonadotropin (hCG). These hormones regulate crucial reproductive functions, including ovulation in females and testosterone production in males. Mutations in the LHCGR gene can disrupt these processes, leading to a range of health conditions.

Associated Diseases

• Leydig cell hypoplasia
• Congenital adrenal hyperplasia
• Hypogonadotropic hypogonadism
• Precocious puberty
• Ovarian hyperstimulation syndrome

Did you know?

The LHCGR gene is also responsible for recognizing the hCG hormone, which is produced during pregnancy. This makes it a target for pregnancy tests.