KRIT1

Description

The KRIT1 gene encodes a protein crucial for the development and function of blood vessels. KRIT1 is involved in various cellular processes, including cell adhesion, migration, and signaling. It interacts with other proteins to form complexes that regulate vascular integrity and angiogenesis (the formation of new blood vessels). Mutations in the KRIT1 gene can lead to various vascular abnormalities and diseases.

Associated Diseases

• Cerebral cavernous malformations (CCM)
• Hereditary hemorrhagic telangiectasia (HHT)
• Other vascular abnormalities and diseases

Did you know?

KRIT1 gene mutations are associated with an increased risk of stroke, particularly in younger individuals.