KISS1
Description
KISS1 is a gene that plays a crucial role in the regulation of puberty and reproduction. It encodes a protein called kisspeptin, which acts as a powerful stimulator of the release of gonadotropin-releasing hormone (GnRH) from the hypothalamus. GnRH, in turn, triggers the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary gland, leading to the development of reproductive organs and the onset of puberty. Beyond its role in reproduction, KISS1 has also been implicated in various other physiological processes, including stress response, metabolism, and cancer.
Associated Diseases
Did you know?
Kisspeptin was originally discovered as a metastasis suppressor in melanoma, but its role in reproductive function was subsequently revealed.
