KCNJ13
Description
The KCNJ13 (potassium inwardly rectifying channel subfamily J member 13) is a protein-coding gene located on chromosome 2.
KCNJ13 is a human gene that codes for the Kir7.1 protein, a type of potassium channel known as an inward rectifier. These channels allow potassium ions to flow more easily into the cell than out of it. This gene is related to the broader category of inward-rectifier potassium ion channels.
KCNJ13 encodes the Kir7.1 protein, a type of inward rectifier potassium channel. These channels preferentially allow potassium ions to flow into the cell. Their behavior is influenced by the concentration of potassium outside the cell; as this concentration increases, the voltage required to open the channel shifts towards more positive values. The inward rectification, the channel's preference for inward potassium flow, is primarily attributed to the blocking of outward current by magnesium ions inside the cell. KCNJ13 exhibits a remarkably low conductance, is minimally affected by external barium and cesium, and its inward rectification is independent of magnesium.
KCNJ13 is also known as KIR1.4, KIR7.1, LCA16, SVD.
