KCNJ1 : potassium inwardly rectifying channel subfamily J member 1
Description
The KCNJ1 (potassium inwardly rectifying channel subfamily J member 1) is a protein-coding gene located on chromosome 11.
The KCNJ1 gene codes for potassium channels that transport potassium ions into and out of cells, playing a crucial role in cell signaling. Specifically, the KCNJ1 protein, also known as ROMK, is primarily found in the kidneys where it regulates potassium ion movement. This regulation is vital for the function of another transporter, NKCC2, which reabsorbs salt from urine back into the bloodstream. This salt retention impacts fluid levels and contributes to blood pressure maintenance.
KCNJ1 is also known as KIR1.1, ROMK, ROMK1.
