ISCU : iron-sulfur cluster assembly enzyme
Description
The ISCU gene encodes a protein known as iron-sulfur cluster scaffold protein. These clusters are essential cofactors for a vast array of cellular processes, including respiration, DNA replication, and amino acid metabolism. ISCU acts as a crucial scaffold during the assembly of these iron-sulfur clusters, facilitating the incorporation of iron and sulfur atoms into a specific protein structure. This complex process involves multiple enzymatic steps and protein interactions, and ISCU plays a pivotal role in ensuring efficient and accurate cluster formation. Dysregulation of ISCU function can have profound consequences for cellular health, leading to various diseases.
Associated Diseases
Did you know?
ISCU is a highly conserved gene, meaning its sequence and function are similar across many different species, highlighting its fundamental importance in cellular biology.
