IL6R
Description
The IL6R gene, encodes for the interleukin-6 receptor (IL-6R), a protein that plays a crucial role in the immune system and inflammatory responses. When IL-6 binds to IL-6R, it triggers a signaling cascade that leads to the production of various inflammatory mediators, contributing to both protective and detrimental effects in the body.
Associated Diseases
- Rheumatoid arthritis
- Crohn‘s disease
- Ulcerative colitis
- Systemic lupus erythematosus
- Multiple sclerosis
- Cancer
- Cardiovascular disease
Did you know?
IL-6R exists in two forms: a membrane-bound form and a soluble form. The soluble form can act as a decoy receptor, binding to IL-6 and preventing it from activating the membrane-bound receptor.
