HOXA1

Description

The HOXA1 gene is a crucial player in the intricate symphony of human development. This gene belongs to the HOX family, a group of genes responsible for directing the formation of the body plan during embryogenesis. HOXA1, specifically, governs the development of the head and neck regions, influencing the formation of critical structures like the brain, face, and spinal cord. Its role is so fundamental that disruptions in HOXA1 can lead to severe developmental abnormalities. Understanding this gene‘s function is crucial for unraveling the complexities of human development and deciphering the origins of various congenital conditions.

Associated Diseases

• Syndrome of the first branchial arch
• Craniofacial malformations
• Spinal cord defects
• Cancer (Leukemia, breast cancer)
• Neurodevelopmental disorders

Did you know?

HOXA1 is a ‘master switch‘ gene, influencing the expression of many other genes involved in development.